Developmental Increase in Hippocampal Endocannabinoid Mobilization : Role of 1 Metabotropic Glutamate Receptor Subtype 5 and Phospholipase C
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چکیده
Word counts: 14 Abstract: 248 15 Introduction: 754 16 Discussion: 1745 17 Pages: 35 18 Figures: 6 black and white 19 20 * Corresponding author: 21 Shu-Ling Liang, Ph.D. 22 Department of Physiology and Pharmacology 23 Chang Gung University 24 259 Wen-Hwa 1st Road, Kwei-Shan, 25 Tao-Yuan, 33302, Taiwan 26 Phone: +886-3-2118800 ext. 3688 27 Fax: +886-3-2118700 28 E-mail: [email protected] 29 30
منابع مشابه
Developmental increase in hippocampal endocannabinoid mobilization: role of metabotropic glutamate receptor subtype 5 and phospholipase C.
Endocannabinoids (eCBs) released from postsynaptic neurons mediate retrograde suppression of neurotransmitter release at central synapses. eCBs are crucial for establishing proper synaptic connectivity in the developing nervous system. Mobilization of eCBs is driven either by a rise in intracellular Ca(2+) (depolarization-induced suppression of inhibition, DSI) or postsynaptic G protein-coupled...
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